Spindle Geometry at Michael Blackwell blog

Spindle Geometry. Architectural integrity of the mitotic spindle is required for efficient chromosome congression and accurate chromosome. On the basis of the data presented here, we propose that spatiotemporally controlled myosin flows in conjunction with spindle. A spindle’s geometry affects its balance, speed capabilities, and how much load it can handle. They are carefully calculated to match the needs of the machine and the work it will do. The goal is to design a spindle that minimizes vibration and maximizes precision. A prime suspect is spindle geometry since previous reports correlated spindle asymmetry and positioning with sibling cell size asymmetry 48,49,50. The shape and size of a spindle are not random. The formation and geometry of the spindle are critical to allow it to correctly segregate the chromosomes.

Wilwood ProSpindle and bump steer
from www.pro-touring.com

A prime suspect is spindle geometry since previous reports correlated spindle asymmetry and positioning with sibling cell size asymmetry 48,49,50. Architectural integrity of the mitotic spindle is required for efficient chromosome congression and accurate chromosome. On the basis of the data presented here, we propose that spatiotemporally controlled myosin flows in conjunction with spindle. A spindle’s geometry affects its balance, speed capabilities, and how much load it can handle. The shape and size of a spindle are not random. The goal is to design a spindle that minimizes vibration and maximizes precision. They are carefully calculated to match the needs of the machine and the work it will do. The formation and geometry of the spindle are critical to allow it to correctly segregate the chromosomes.

Wilwood ProSpindle and bump steer

Spindle Geometry Architectural integrity of the mitotic spindle is required for efficient chromosome congression and accurate chromosome. On the basis of the data presented here, we propose that spatiotemporally controlled myosin flows in conjunction with spindle. The goal is to design a spindle that minimizes vibration and maximizes precision. The shape and size of a spindle are not random. The formation and geometry of the spindle are critical to allow it to correctly segregate the chromosomes. Architectural integrity of the mitotic spindle is required for efficient chromosome congression and accurate chromosome. A spindle’s geometry affects its balance, speed capabilities, and how much load it can handle. A prime suspect is spindle geometry since previous reports correlated spindle asymmetry and positioning with sibling cell size asymmetry 48,49,50. They are carefully calculated to match the needs of the machine and the work it will do.

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